The Kröller-Müller Museum is world-famous for its large collection of paintings by Vincent van Gogh: it features a magnificent selection of his work. The museum also houses impressive works by George Seurat, Pablo Picasso, Fernand Leger, Piet Mondriaan and many other leading artists.

Temporary exhibitions are regularly staged featuring works from the 20th century and contemporary art, and retrospectives are staged. These are devoted to important artists, with works from the Museum's own collection on display. Works from the Museum's sculpture collection are also regularly displayed in rooms in the new wing of the Museum. These include works by Donald Judd, Alberto Giacometti, Sol LeWitt, Bruce Nauman and others.

Another famous feature of the Kröller-Müller Museum is the sculpture garden - the largest such garden in Europe. A magnificent collection of sculpture is displayed in an unusual setting, surrounded by nature. Various artists from the end of the 19th century to the present day are presented: Auguste Rodin, Henry Moore, Barbara Hepworth, Richard Serra, Mario Merz, Jean Dubuffet and Claes Oldenburg.